tailieunhanh - Báo cáo y học: " Nail changes secondary to docetaxel chemotherapy : a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Nail changes secondary to docetaxel chemotherapy : a case report. | Journal of Medical Case Reports BioMed Central Open Access Case report Nail changes secondary to docetaxel chemotherapy a case report Qamar Ghafoor and Anula Chetiyawardana Address University Hospital Birmingham Birmingham UK Email Qamar Ghafoor - Anula Chetiyawardana - Corresponding author Published 28 January 2008 Received 26 September 2007 Journal of Medical Case Reports 2008 2 24 doi 1752-1947-2-24 Accepted 28 January 2008 This article is available from http content 2 1 24 2008 Ghafoor and Chetiyawardana licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Docetaxel is a chemotherapy agent used in the management of many neoplastic conditions. Various side effects are known. Nail changes are often under-recognised or attributed to other causes. Case presentation We report the case of a 66 year old gentleman who received docetaxel chemotherapy for non-small cell lung cancer. He had nail changes as a complication of the treatment. Conclusion Nail toxicity is a recognised side-effect of taxane chemotherapy agents and can often persist for many months after finishing the treatment. We would like to highlight this problem so it can be considered as a differential diagnosis in the appropriate population. Introduction Docetaxel is a chemotherapy agent used in the management of many neoplastic conditions. These malignant diseases would include lung breast ovary head and neck and prostate cancer 1 2 . There are various schedules for administering the drug including weekly and threeweekly. Nail changes are known to happen with all of these schedules. Docetaxel is a semisynthetic taxane derived from the needles of the .

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