tailieunhanh - Báo cáo y học: "An unusual presentation of multiple myeloma: a case report."

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An unusual presentation of multiple myeloma: a case report. | Journal of Medical Case Reports BioMed Central Case report Open Access An unusual presentation of multiple myeloma a case report Catherine B Molloy 1 2 Rahul A Peck2 Stephen J Bonny3 Simon N Jowitt3 4 John Denton5 Anthony J Freemont5 and Abbas A Ismail2 Address Rheumatology St. Michaels Hospital Toronto Canada 2Rheumatology Stockport NHS Trust UK 3Haematology Stockport NHS Trust UK 4Haematology Salford Royal NHS Trust UK and 5Osteoarticular Pathology Manchester University UK Email Catherine B Molloy - catherine_molloy@ Rahul A Peck - Stephen J Bonny - sjbonny@ Simon N Jowitt - John Denton - Anthony J Freemont - Abbas A Ismail - Corresponding author Published 10 September 2007 Received 16 June 2007 -. I Accepted 10 September 2007 Journal of Medical Case Reports 2007 1 84 doi 86 1752-1947-1-84 This article is available from http content 1 1 84 2007 Molloy et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Multiple myeloma can occasionally manifest with joint disease. We report the case of an individual with a progressive bilateral carpal syndrome and a symmetrical severe seronegative polyarthritis and joint swelling. Investigations revealed an erosive seronegative inflammatory arthritis in association with bilateral carpal tunnel syndrome anaemia hepatic impairment and nephrotic-range proteinuria. Synovial fluid cytology demonstrated plasmablasts and multinucleated cells with products of chondrolysis. The diagnosis of multiple myeloma with secondary amyloidosis was made on serum protein .