tailieunhanh - Báo cáo y học: "Current problems of perinatal Chlamydia trachomatis infections"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Current problems of perinatal Chlamydia trachomatis infections. | Journal of Immune Based Therapies and Vaccines BioMed Central Review Open Access Current problems of perinatal Chlamydia trachomatis infections Kei Numazaki Address Department of Pediatrics Sapporo Medical University School of Medicine Sapporo Japan Email Kei Numazaki - numazaki@ Corresponding author Published 13 February 2004 Received 29 July 2003 Journal of Immune Based Therapies and Vaccines 2004 2 4 This article is available from http content 2 1 4 Accepted 13 February 2004 2004 Numazaki licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Chlamydia trachomatis has been recognized as a pathogen of trachoma nongonococcal urethritis salpingitis endocervicitis pelvic inflammatory disease inclusion conjunctivitis of neonates follicular conjunctivitis of adults infantile pneumonia and associated conditions. Chlamydial infections during pregnancy may also cause a variety of perinatal complications. Different antigenic strains of C. trachomatis from endocervical nasopharyngeal and conjunctival origins have been associated with different clinical conditions. Control programs emphasizing early diagnosis targeted screening and effective treatment will lead to an eventual decline in the incidence of perinatal chlamydial infection. This review focuses on current problems of perinatal C. trachomatis infections in the aspects of microbiological and immunological pathogenesis. Introduction Chlamydiae are obligate intracellular bacteria that have been associated with a wide spectrum of human diseases. Currently they can be divided into four groups C. trachomatis C. psittaci C. pneumoniae and C. pecorum. C. trachomatis is the causal agent of trachoma which is an important cause of blindness and affects approximately 500 million people mainly in developing .