tailieunhanh - Báo cáo khoa học: "Predicting late anemia in critical illness"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Predicting late anemia in critical illness. | Available online http content 10 1 R39 Open Access Research Predicting late anemia in critical illness Eric B Milbrandt Gilles Clermont Javier Martinez Alex Kersten Malik T Rahim and Derek C Angus The CRISMA Laboratory Clinical Research Investigation and Systems Modeling of Acute Illness Department of Critical Care Medicine University of Pittsburgh School of Medicine 3550 Terrace Street Pittsburgh PA 15261 USA Corresponding author Gilles Clermont clermontg@ Received 6 Dec 2005 Revisions requested 5 Jan 2006 Revisions received 3 Feb 2006 Accepted 9 Feb 2006 Published 28 Feb 2006 Critical Care 2006 10 R39 doi cc4847 This article is online at http content 10 1 R39 2006 Milbrandt et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Identifying critically ill patients most likely to benefit from pre-emptive therapies will become increasingly important if therapies are to be used safely and cost-effectively. We sought to determine whether a predictive model could be constructed that would serve as a useful decision support tool for the preemptive management of intensive care unit ICU -related anemia. Methods Our cohort consisted of all ICU patients n 5 170 admitted to a large tertiary-care academic medical center during the period from 1 July 2000 to 30 June 2001. We divided the cohort into development n 3 619 and validation n 1 551 sets. Using a set of demographic and physiologic variables available within six hours of ICU admission we developed models to predict patients who either received late transfusion or developed late anemia. We then constructed a point system to quantify within six hours of ICU admission the likelihood of developing late anemia. Results .

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