tailieunhanh - Báo cáo khoa học: "Cutaneous vascular reactivity and flow motion response to vasopressin in advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndrome"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cutaneous vascular reactivity and flow motion response to vasopressin in advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndrome. | Available online http content 10 2 R40 Research Cutaneous vascular reactivity and flow motion response to vasopressin in advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndrome Gunter Luckner1 Martin W Dunser1 Karl-Heinz Stadlbauer1 Viktoria D Mayr1 Stefan Jochberger1 Volker Wenzel1 Hanno Ulmer2 Werner Pajk1 Walter R Hasibeder3 Barbara Friesenecker1 and Hans Knotzer1 Open Access department of Anesthesiology Innsbruck Medical University Innsbruck Austria department of Biostatistics and Documentation Innsbruck Medical University Innsbruck Austria department of Anesthesiology and Critical Care Medicine Krankenhaus der Barmherzigen Schwestern Ried im Innkreis Austria Corresponding author Martin W Dunser Received 25 Oct 2005 Revisions requested 5 Nov 2005 Revisions received 28 Dec 2005 Accepted 7 Feb 2006 Published 7 Mar 2006 Critical Care 2006 10 R40 doi cc4845 This article is online at http content 10 2 R40 2006 Luckner et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Disturbances in mieroeireulatory homeostasis have been hypothesized to play a key role in the pathophysiology of multiple organ dysfunction syndrome and vasopressor-associated ischemic skin lesions. The effects of a supplementary arginine vasopressin AVP infusion on microcirculation in vasodilatory shock and postoperative multiple organ dysfunction syndrome are unknown. Method Included in the study were 18 patients who had undergone cardiac or major surgery and had a mean arterial blood pressure below 65 mmHg despite infusion of more than pg kg per min norepinephrine. Patients were randomly assigned to receive a combined infusion of AVP .

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