tailieunhanh - Báo cáo khoa học: "Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: an observational study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: an observational study. | Available online http content 9 6 R816 Research Mid-regional pro-adrenomedullin as a prognostic marker in sepsis an observational study Mirjam Christ-Crain1 Nils G Morgenthaler2 Joachim Struck3 Stephan Harbarth4 Andreas Bergmann5 and Beat Muller6 Open Access Department of Internal Medicine University Hospital Basel Petersgraben 4 4031 Basel Switzerland 2Research Department Brahms AG Hennigsdorf Berlin Neuendorfstrasse 25 16761 Hennigsdorf Germany 3Research Department Brahms AG Hennigsdorf Berlin Neuendorfstrasse 25 16761 Hennigsdorf Germany 4Division of Hospital Epidemiology University Hospital Geneva 24 rue Micheli-du-Crest 1211 Geneva 14 Switzerland 5Research Department Brahms AG Hennigsdorf Berlin Neuendorfstrasse 25 16761 Hennigsdorf Germany 6Department of Internal Medicine University Hospital Basel Petersgraben 4 4031 Basel Switzerland Corresponding author Beat Muller Received 10 May 2005 Revisions requested 13 Jun 2005 Revisions received 22 Sep 2005 Accepted 29 Sep 2005 Published 15 Nov 2005 Critical Care 2005 9 R816-R824 DOI 86 cc3885 This article is online at http content 9 6 R816 2005 Christ-Crain et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Measurement of biomarkers is a potential approach to early assessment and prediction of mortality in patients with sepsis. The aim of the present study was to evaluate the prognostic value of mid-regional pro-adrenomedullin MR-proADM levels in a cohort of medical intensive care patients and to compare it with other biomarkers and physiological scores. Method We evaluated blood samples from 101 consecutive critically ill patients admitted to the intensive care unit and from 160 age-matched .