tailieunhanh - Báo cáo y học: " Modification of a loop sequence between -helices 6 and 7 of virus capsid (CA) protein in a human "

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Retrovirology cung cấp cho các bạn kiến thức về ngành y đề tài: " Modification of a loop sequence between -helices 6 and 7 of virus capsid (CA) protein in a human . | Retrovirology BioMed Central Research Modification of a loop sequence between a-helices 6 and 7 of virus capsid CA protein in a human immunodeficiency virus type 1 HIV-1 derivative that has simian immunodeficiency virus SIVmac239 vif and CA a-helices 4 and 5 loop improves replication in cynomolgus monkey cells Ayumu Kuroishi1 Akatsuki Saito2 Yasuhiro Shingai1 Tatsuo Shioda1 Masako Nomaguchi3 Akio Adachi3 Hirofumi Akari2 and Emi E Nakayama 1 Open Access Address Department of Viral Infections Research Institute for Microbial Diseases Osaka University Osaka 565-0871 Japan 2Tsukuba Primate Research Center National Institute of Biomedical Innovation Ibaraki 305-0843 Japan and 3Department of Virology Institute of Health Biosciences University of Tokushima Graduate School Tokushima 770-8503 Japan Email Ayumu Kuroishi - kuroishi@ Akatsuki Saito - a-saito@ Yasuhiro Shingai - chokobo918@ Tatsuo Shioda - shioda@ Masako Nomaguchi - nomaguchi@ Akio Adachi - adachi@ Hirofumi Akari - akari@ Emi E Nakayama - emien@ Corresponding author Published 3 August 2009 Received 12 March 2009 Retrovirology 2009 6 70 doi 1742-4690-6-70 Accepted 3 August 2009 This article is available from http content 6 1 70 2009 Kuroishi et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background Human immunodeficiency virus type 1 HIV-1 productively infects only humans and chimpanzees but not cynomolgus or rhesus monkeys while simian immunodeficiency virus isolated from macaque SIVmac readily .