tailieunhanh - Báo cáo khoa học: "Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection. | Available online http content 9 5 R483 Research Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection Michael Siassi1 Jutta Riese1 Rudi Steffensen2 Michael Meisner3 Steffen Thiel4 Werner Hohenberger5 and Joachim Schmidt6 Department of Surgery University Hospital Erlangen Erlangen Germany 2Regional Centre for Blood Transfusion and Clinical Immunology Aalborg Hospital Aalborg Denmark 3Department of Anaesthesiology University Hospital Jena Jena Germany 4Department of Medical Microbiology and Immunology University of Aarhus Aarhus Denmark 5Professor Department of Surgery University Hospital Erlangen Erlangen Germany 6Department of Anaesthesiology University Hospital Erlangen Erlangen Germany Corresponding author Michael Siassi michael@ Received 2 May 2005 Revisions requested 27 May 2005 Revisions received 7 Jun 2005 Accepted 20 Jun 2005 Published 19 Jul 2005 Critical Care 2005 9 R483-R489 DOI 86 cc3768 This article is online at http content 9 5 R483 2005 Siassi et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Postoperative infection is a major cause of morbidity and mortality. We investigated two serum markers for their ability to identify patients at risk for postoperative infection. Mannan-binding lectin MBL is a central molecule of the innate immune system and MBL deficiency is known to predispose to infection. Procalcitonin PCT is a sensitive marker for bacterial infection. Methods We investigated 162 patients undergoing elective surgery for cancer of the gastrointestinal tract. Patients were classified as having no complications group A having infection for unknown reason group B or having sepsis after .