tailieunhanh - Báo cáo khoa học: "Efficiency of 7.2% hypertonic saline hydroxyethyl starch 200/0.5 versus mannitol 15% in the treatment of increased intracranial pressure in neurosurgical patients – a randomized clinical trial [ISRCTN62699180]"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Efficiency of hypertonic saline hydroxyethyl starch 200/ versus mannitol 15% in the treatment of increased intracranial pressure in neurosurgical patients – a randomized clinical trial [ISRCTN62699180]. | Available online http content 9 5 R530 Research Efficiency of hypertonic saline hydroxyethyl starch 200 versus mannitol 15 in the treatment of increased intracranial pressure in neurosurgical patients - a randomized clinical trial ISRCTN62699180 Lilit Harutjunyan1 Carsten Holz2 Andreas Rieger2 Matthias Menzel3 Stefan Grond4 and Jens Soukup5 1Anaesthesiologist Department of Anesthesia and Critical Care Martin-Luther-University Halle-Wittenberg Halle Germany 2Neurosurgeon Department of Neurosurgery Martin-Luther-University Halle-Wittenberg Halle Germany 3Head Department of Anesthesia and Critical Care Klinikum Wolfsburg Wolfsburg Germany 4Professor of Anesthesiology and Pain Therapy Department of Anesthesia and Critical Care Martin-Luther-University Halle-Wittenberg Halle Germany 5Anaesthesiologist and Intensivist Department of Anesthesia and Critical Care Martin-Luther-University Halle-Wittenberg Halle Germany Corresponding author Lilit Harutjunyan arlilith@ Received 6 May 2005 Revisions requested 6 Jun 2005 Revisions received 14 Jun 2005 Accepted 17 Jun 2005 Published 9 Aug 2005 Critical Care 2005 9 R530-R540 DOI 86 cc3767 This article is online at http content 9 5 R530 2005 Harutjunya et al. licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction This prospective randomized clinical study investigated the efficacy and safety of hypertonic saline hydroxyethyl starch 200 NaCl HES 200 in comparison with 15 mannitol in the treatment of increased intracranial pressure ICP . Methods Forty neurosurgical patients at risk of increased ICP were randomized to receive either NaCl HES 200 or 15 mannitol at a defined infusion rate which was .

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