tailieunhanh - Báo cáo khoa học: "Is it time to increase the frequency of use of high-frequency oscillatory ventilation"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Is it time to increase the frequency of use of high-frequency oscillatory ventilation? | Available online http content 9 4 339 Commentary Is it time to increase the frequency of use of high-frequency oscillatory ventilation Jeffrey M Singh1 and Niall D Ferguson2 1 Lecturer Interdepartmental Division of Critical Care Medicine and Department of Medicine Division of Respirology University Health Network University of Toronto Toronto Ontario Canada 2Assistant Professor Interdepartmental Division of Critical Care Medicine and Department of Medicine Division of Respirology University Health Network University of Toronto Toronto Ontario Canada Corresponding author ND Ferguson Published online 24 June 2005 Critical Care 2005 9 339-340 DOI cc3761 This article is online at http content 9 4 339 2005 BioMed Central Ltd See related research article by Bollen et al. in this issue http ccforum content 9 4 R430 Abstract In this issue of Critical Care Bollen and colleagues present the results of a multicentre randomised controlled trial comparing high-frequency oscillatory ventilation with conventional ventilation as the primary ventilation mode for adults with acute respiratory distress syndrome. The study was stopped early after recruiting only 61 patients because of declining enrolment and although no differences were detected in any primary or secondary endpoint this trial only had sufficient power to detect extreme differences in outcomes between groups. This editorial attempts to put these results in context with previous work and highlights challenges to be addressed in future studies. Recognition of the impact of ventilator-induced lung injury on morbidity and mortality in patients with acute respiratory distress syndrome ARDS has led to an ongoing search for ventilation strategies that limit further damage to the already injured lung. In this issue of Critical Care Bollen and colleagues 1 present the results of a multicentre randomised controlled trial comparing high-frequency oscillatory ventilation HFOV