tailieunhanh - Báo cáo khoa học: "Clinical review: Mechanical ventilation in severe asthm"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Clinical review: Mechanical ventilation in severe asthma. | Available online http content 9 6 581 Review Clinical review Mechanical ventilation in severe asthma David R Stather1 and Thomas E Stewart2 1 Fellow InterDepartmental Division of Critical Care Medicine and Division of Respirology Department of Medicine Mount Sinai Hospital and University Health Network University of Toronto Toronto Canada 2Associate Professor Department of Medicine and Anaesthesia and Administrative Director Critical Care Medicine Mount Sinai Hospital and University Health Network University of Toronto Toronto Canada Corresponding author Thomas E Stewart tstewart@ Published online 8 September 2005 This article is online at http content 9 6 581 2005 BioMed Central Ltd Critical Care 2005 9 581-587 DOI cc3733 See related letter by Cole online http content 9 6 E29 Abstract Respiratory failure from severe asthma is a potentially reversible life-threatening condition. Poor outcome in this setting is frequently a result of the development of gas-trapping. This condition can arise in any mechanically ventilated patient but those with severe airflow limitation have a predisposition. It is important that clinicians managing these types of patients understand that the use of mechanical ventilation can lead to or worsen gas-trapping. In this review we discuss the development of this complication during mechanical ventilation techniques to measure it and strategies to limit its severity. We hope that by understanding such concepts clinicians will be able to reduce further the poor outcomes occasionally related to severe asthma. Introduction Asthma continues to inflict significant morbidity and mortality worldwide. Despite advances in therapy and in our understanding of its pathophysiology the prevalence of asthma is increasing 1-3 although there is significant age and geographic variation 4 . While the prevalence of asthma has increased outcomes of severe asthma appear to be improving with lower .

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