tailieunhanh - Báo cáo khoa học: "Can mupirocin prevent methicillin-resistant Staphylococcus aureus infection"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Can mupirocin prevent methicillin-resistant Staphylococcus aureus infections? | Available online http content 9 3 257 Commentary Can mupirocin prevent methicillin-resistant Staphylococcus aureus infections Heiman FL Wertheim and Margreet C Vos Erasmus MC Department of Medical Microbiology and Infectious Disease Rotterdam The Netherlands Corresponding author Heiman Wertheim Published online 5 May 2005 This article is online at http content 9 3 257 2005 BioMed Central Ltd Critical Care 2005 9 257-258 DOI cc3720 See related research by Muller et al. in this issue http content 9 3 R246 Abstract In a retrospective study Dr Muller and colleagues have assessed the efficacy of mupirocin nasal ointment alongside hygienic measures in methicillin-resistant Staphylococcus aureus MRSA -positive patients admitted to the intensive care unit ICU . Their findings which suggest that intranasal mupirocin can prevent ICU-related MRSA infections need confirmation in a well-designed clinical trial. In general early identification isolation and treatment of all MRSA carriers including health care workers and disinfection of contaminated environments are the main ingredients of an effective MRSA search and destroy program. In this issue of Critical Care AA Muller and colleagues present a study in which they assessed the efficacy of mupirocin nasal ointment in preventing methicillin-resistant Staphylococcus aureus MRSA infections in an intensive care unit ICU 1 . MRSA constitutes a special problem with regard to the prevention and treatment of infection. Studies show that MRSA carriers have a higher risk of nosocomial infection with this microorganism and that those infected with MRSA have a greater morbidity and mortality than those infected with susceptible strains 2 3 . It is therefore important to keep the prevalence of MRSA carriage and MRSA infections low. Efforts to achieve this should be supported. Muller and colleagues performed a retrospective study in which they compared a 2-year MRSA .