tailieunhanh - Báo cáo khoa học: "Meta-analysis of hemodynamic optimization: relationship to methodological quality"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Meta-analysis of hemodynamic optimization: relationship to methodological quality. | Available online http content 9 6 R771 Open Access Research Meta-analysis of hemodynamic optimization relationship to methodological quality Martijn Poeze Jan Willem M Greve and Graham Ramsay Department of Surgery University Hospital Maastricht P Debyelaan 25 6202 AZ Maastricht The Netherlands Corresponding author Martijn Poeze Received 14 Apr 2005 Revisions requested 25 May 2005 Revisions received 17 Sep 2005 Accepted 13 Oct 2005 Published 15 Nov 2005 Critical Care 2005 9 R771-R779 DOI cc3902 This article is online at http content 9 6 R771 2005 Poeze et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction To review systematically the effect of interventions aimed at hemodynamic optimization and to relate this to the quality of individual published trials. Methods A systematic computerized bibliographic search of published studies and citation reviews of relevant studies was performed. All randomized clinical trials in which adult patients were included in a trial deliberately aiming at an optimized or maximized hemodynamic condition of the patients with oxygen delivery cardiac index oxygen consumption mixed venous oxygen saturation and or stroke volume as end-points were selected. A total of 30 studies were selected for independent review. Two reviewers extracted data on population intervention outcome and methodological quality. Agreement between reviewers was high differences were eventually resolved by third-party decision. The methodological quality of the studies was moderate mean SD and the outcomes of the randomized clinical trials were not related to their quality. Results Efforts to achieve an optimized hemodynamic condition .

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