tailieunhanh - MENINGIOMAS – MANAGEMENT AND SURGERY

Second, it should not be forgot that several neuroprotectant have failed not because they lacked efficacy, but because they revealed unexpected side effects. Many NMDAreceptor antagonists were discarded because in clinical trials they showed psychedelic unwanted effects. Tirilazad, an antioxidant belonging to the “lazaroid” class of antioxidants, unexpectedly worsened outcome of ischemic stroke, a fact very likely explained by some unexpected toxic action(s) that offset its neuroprotective ability. So, the 21st century will hopefully favor the harmonization of basic research and of clinical neurology, two realities that were too distant from each other in the second half of the 20th century. Hopefully, preclinical scientists will learn how to. | MENINGIOMAS - MANAGEMENT AND SURGERY Edited by Daniel Monleon Meningiomas - Management and Surgery Edited by Daniel Monleon Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Maja Kisic Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February 2012 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Meningiomas - Management and Surgery Edited by Daniel Monleon p. cm. 978-953-51-0175-8 INTECH open science I open minds free online editions of InTech Books and Journals can be .