tailieunhanh - Báo cáo hóa học: " Structural and physical properties of antibacterial Ag-doped nano-hydroxyapatite synthesized at 100°C"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa hoc quốc tế đề tài : Structural and physical properties of antibacterial Ag-doped nano-hydroxyapatite synthesized at 100°C | Ciobanu et al. Nanoscale Research Letters 2011 6 613 http content 6 1 613 o Nanoscale Research Letters a SpringerOpen Journal NANO EXPRESS Open Access Structural and physical properties of antibacterial Ag-doped nano-hydroxyapatite synthesized at 100 C Carmen Steluta Ciobanu 1 Florian Massuyeau2 Liliana Violeta Constantin3 and Daniela Predoi1 Abstract Synthesis of nanosized particle of Ag-doped hydroxyapatite with antibacterial properties is in the great interest in the development of new biomedical applications. In this article we propose a method for synthesized the Ag-doped nanocrystalline hydroxyapatite. A silver-doped nanocrystalline hydroxyapatite was synthesized at 100 C in deionized water. Other phase or impurities were not observed. Silver-doped hydroxyapatite nanoparticles Ag HAp were performed by setting the atomic ratio of Ag Ag Ca at 20 and Ca Ag P as . The X-ray diffraction studies demonstrate that powders made by co-precipitation at 100 C exhibit the apatite characteristics with good crystal structure and no new phase or impurity is found. The scanning electron microscopy SEM observations suggest that these materials present a little different morphology which reveals a homogeneous aspect of the synthesized particles for all samples. The presence of calcium Ca phosphor P oxygen O and silver Ag in the Ag HAp is confirmed by energy dispersive X-ray EDAX analysis. FT-IR and FT-Raman spectroscopies revealed that the presence of the various vibrational modes corresponds to phosphates and hydroxyl groups. The strain of Staphylococcus aureus was used to evaluate the antibacterial activity of the Ca10-xAgx PO4 6 OH 2 x 0 and . In vitro bacterial adhesion study indicated a significant difference between HAp x 0 and Ag HAp x . The Ag Hap nanopowder showed higher inhibition. 1. Introduction Inorganic biomaterials based on calcium orthophosphate have their wide range of applications in medicine 1-4 . Among them synthetic .