tailieunhanh - Báo cáo y học: ": Suppression of neutrophil accumulation in mice by cutaneous application of geranium essential oi"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Suppression of neutrophil accumulation in mice by cutaneous application of geranium essential oil. | Journal of Inflammation BioMed Central Research Open Access Suppression of neutrophil accumulation in mice by cutaneous application of geranium essential oil Naho Maruyama1 Yuka Sekimoto1 2 Hiroko Ishibashi1 Shigeharu Inouye1 Haruyuki Oshima2 Hideyo Yamaguchi1 and Shigeru Abe 1 Address 1Teikyo University Institute of Medical Mycology 359 Otsuka Hachioji Tokyo 192-0395 Japan and 2Department of Bioengineering Faculty of Technology Teikyo University 1-1 Toyosato-dai Utsunomiya Tochigi 320-0003 Japan Email Naho Maruyama - sabe@ Yuka Sekimoto - sabe@ Hiroko Ishibashi - sabe@ Shigeharu Inouye - sabe@ Haruyuki Oshima - sabe@ Hideyo Yamaguchi - sabe@ Shigeru Abe - sabe@ Corresponding author Published 10 February 2005 Journal of Inflammation 2005 2 1 doi 186 1476-9255-2-1 Received 04 October 2004 Accepted 10 February 2005 This article is available from http content 2 1 1 2005 Maruyama et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Previous studies suggested that essential oils suppressed the adherence response of human neutrophils in vitro and that intraperitoneal application of geranium oil suppressed the neutrophil accumulation into peritoneal cavity in vivo. Usually essential oils are applied through skin in aromatherapy in inflammatory symptoms. The purpose of this study is to assess the effects of cutaneous application of essential oils on the accumulation of neutrophils in inflammatory sites in skin of mice. Methods Inflammation with accumulation of inflammatory cells was induced by injection of curdlan a 1 3 -P-D-glucan in skin or .