tailieunhanh - Báo cáo hóa học: " Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa hoc quốc tế đề tài : Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications | Ghoshal et al. Nanoscale Research Letters 2011 6 540 http content 6 1 540 o Nanoscale Research Letters a SpringerOpen Journal NANO EXPRESS Open Access Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications 11 1 I- c- z- t-s 2 1 1 2 Sarmishtha Ghoshal Abul AM Ansar Sufi O Raja Arpita Jana Nil R Bandyopadhyay Anjan K Dasgupta and Mallar Ray Abstract A uniformly distributed array of micro test tubes and microbeakers is formed on a p-type silicon substrate with tunable cross-section and distance of separation by anodic etching of the silicon wafer in N N-dimethylformamide and hydrofluoric acid which essentially leads to the formation of macroporous silicon templates. A reasonable control over the dimensions of the structures could be achieved by tailoring the formation parameters primarily the wafer resistivity. For a micro test tube the cross-section . the pore size as well as the distance of separation between two adjacent test tubes . inter-pore distance is typically approximately 1 pm whereas for a microbeaker the pore size exceeds pm and the inter-pore distance could be less than 100 nm. We successfully synthesized superparamagnetic iron oxide nanoparticles SPIONs with average particle size approximately 20 nm and attached them on the porous silicon chip surface as well as on the pore walls. Such SPION-coated arrays of micro test tubes and microbeakers are potential candidates for biosensors because of the biocompatibility of both silicon and SPIONs. As acquisition of data via microarray is an essential attribute of high throughput bio-sensing the proposed nanostructured array may be a promising step in this direction. Keywords porous silicon SPION biosensor Introduction The promotion of silicon Si from being the key substrate material for microelectronic devices to a potential light emitter emerged as a consequence of the .