tailieunhanh - Báo cáo y học: " Papanicolaou smears and cervical inflammatory cytokine responses"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Papanicolaou smears and cervical inflammatory cytokine responses. | Journal of Inflammation BioMed Central Research Open Access Papanicolaou smears and cervical inflammatory cytokine responses Jo-Ann S Passmore 1 Chelsea Morroni2 Samual Shapiro3 Anna-Lise Williamson1 4 and Margaret Hoffman2 Address 1Division of Medical Virology Institute of Infectious Disease and Molecular Medicine Faculty of Health Sciences University of Cape Town Cape Town South Africa 2Women s Health Research Unit School of Public Health and Family Medicine Faculty of Health Sciences University of Cape Town Cape Town South Africa 3Department Of Epidemiology Mailman School of Public Health New York USA and 4National Health Laboratory Service Groote Schuur Hospital Observatory Cape Town South Africa Email Jo-Ann S Passmore - Chelsea Morroni - chelsea@ Samual Shapiro - samshap@ Anna-Lise Williamson - annalise@ Margaret Hoffman - mh@ Corresponding author Published 24 April 2007 Received 7 September 2006 Journal of Inflammation 2007 4 8 doi 186 1476-9255-4-8 Accepted 24 April 2007 This article is available from http content 4 1 8 2007 Passmore et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract In a case-control study among 2064 South African women to investigate the risk of clinically invasive cancer of the cervix we found a marked reduction in the risk of cervical cancer among women who gave a history of ever having undergone even a single Pap smear and a statistically significant decline in the HPV positivity rate correlated with the lifetime number of Pap smears received. HPV infections and their associated low-grade lesions commonly regress indicating that most often there is an effective host