tailieunhanh - Báo cáo y học: "Bronchospasm and laryngeal stridor as an adverse effect of oxytocin treatment"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài: Bronchospasm and laryngeal stridor as an adverse effect of oxytocin treatment. | Critical Care October 2003 Vol 7 No 5 Cabestrero et al. Letter Bronchospasm and laryngeal stridor as an adverse effect of oxytocin treatment David Cabestrero1 Carmen Pérez-Paredes1 Ramón Fernández-Cid2 and Miguel A Arribas1 1Staff Specialist Critical Care Unit Hospital Verge del Toro Mahón Menorca Spain 2Director of Intensive Care Critical Care Unit Hospital Verge del Toro Mahón Menorca Spain Correspondence David Cabestrero cabestrero@ Published online 10 July 2003 Critical Care 2003 7 392 DOI cc2348 This article is online at http content 7 5 392 2003 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Oxytocin is frequently used worldwide. Some of its adverse effects are well known but bronchospasm and laryngeal stridor as anaphylactoid reactions have not yet been reported. Oxytocin is a synthetically prepared hormone that stimulates contractions of uterine smooth muscle and it is used for induction and augmentation of labor as well as in abortions. Adverse effects reported with oxytocin include reflex tachycardia hypotension electrocardiographic changes increased cardiac output myocardial infarction alteration in fetal heart rate seizures headache memory impairment cerebrospinal bleeding hyponatremia syndrome of inappropriate antidiuretic hormone secretion nausea and vomiting uterine rupture neonatal hyperbilirubinemia and anaphylaxis 1 . To our knowledge bronchospasm and laryngeal stridor occur very rarely in oxytocin anaphylaxis. A 41-year-old woman was admitted to our intensive care unit after having a septic abortion in the 18th week of pregnancy. This was her second gestation the first culminating in a cesarean section . After abortion she presented with septic shock oligoanuria consumption coagulopathy and respiratory insufficiency. She was first treated intravenously with crystalloids colloids inotropics furosemide perfusion empirical antibiotics . cefotaxime metronidazol and doxycycline and frozen fresh .