tailieunhanh - Báo cáo y học: "Esophageal capnometry during hemorrhagic shock and after resuscitation in rats"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài: Esophageal capnometry during hemorrhagic shock and after resuscitation in rats. | Available online http content 7 1 79 Research Open Access Esophageal capnometry during hemorrhagic shock and after resuscitation in rats Balagangadhar R Totapally1 Harun Fakioglu2 Dan Torbati3 and Jack Wolfsdorf4 11ntensivist Division of Critical Care Medicine Miami Children s Hospital Miami Florida USA 2Fellow Pediatric Care Medicine Division of Critical Care Medicine Miami Children s Hospital Miami Florida USA 3Associate Professor and Research Director Division of Critical Care Medicine Miami Children s Hospital Miami Florida USA 4Clinical Professor of Pediatric and Director Division of Critical Care Medicine Miami Children s Hospital Miami Florida USA Correspondence Dan Torbati Received 14 August 2002 Revisions requested 15 October 2002 Revisions received 7 November 2002 Accepted 8 November 2002 Published 20 December 2002 Critical Care 2003 7 79-84 DOI cc1856 This article is online at http content 7 1 79 2003 Totapally et al. licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X . This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any non-commercial purpose provided this notice is preserved along with the article s original URL. Abstract Background Splanchnic perfusion following hypovolemic shock is an important marker of adequate resuscitation. We tested whether the gap between esophageal partial carbon dioxide tension PeC02 and arterial partial carbon dioxide tension PaC02 is increased during graded hemorrhagic hypotension and reversed after blood reinfusion using a fiberoptic carbon dioxide sensor. Materials and method Ten Sprague-Dawley rats were anesthetized tracheotomized and cannulated in one femoral artery and vein. A calibrated fiberoptic PCO2 probe was inserted into the distal third of the esophagus for determination of luminal PeCO2 during maintained anesthesia pentobarbital 15mg kg per hour normothermia 38 C and .