tailieunhanh - Báo cáo khoa hoc:" Aortic distensibility measured by pulse-wave velocity is not modified in patients with Chagas' disease"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Aortic distensibility measured by pulse-wave velocity is not modified in patients with Chagas' disease | Journal of Negative Results in BioMedicine BioMed Central Research Aortic distensibility measured by pulse-wave velocity is not modified in patients with Chagas disease Humberto Villacorta1 2 Luiz Aparecido Bortolotto 1 Edmundo Arteaga1 and Charles Mady1 Open Access Address Heart Institute InCor University of São Paulo Medical School São Paulo Brazil and 2Hospital Pró-Cardíaco Rio de Janeiro Brazil Email Humberto Villacorta - huvillacorta@ Luiz Aparecido Bortolotto - hipluiz@ Edmundo Arteaga - earteaga@ Charles Mady - Corresponding author Published 12 June 2006 Received 25 March 2005 Journal of Negative Results in BioMedicine 2006 5 9 doi l 477-5751-5-9 Accepted 12 June 2006 This article is available from http content 5 1 9 2006 Villacorta et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background Experimental studies demonstrate that infection with trypanosoma cruzi causes vasculitis. The inflammatory lesion process could hypothetically lead to decreased distensibility of large and small arteries in advanced Chagas disease. We tested this hypothesis. Methods and results We evaluated carotid-femoral pulse-wave velocity PWV in 53 Chagas disease patients compared with 31 healthy volunteers control group . The 53 patients were classified into 3 groups l l6 with indeterminate form of Chagas disease 2 l8 with Chagas disease electrocardiographic abnormalities and normal systolic function 3 19 with Chagas disease systolic dysfunction and mild-to-moderate congestive heart failure. No difference was noted between the 4 groups regarding carotid-femoral PWV

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