tailieunhanh - Báo cáo y học: "Hypothermia and neurologic outcome in patients following cardiac arrest: should we be hot to cool off our patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài: Hypothermia and neurologic outcome in patients following cardiac arrest: should we be hot to cool off our patients? | Available online http content 6 5 377 Commentary Hypothermia and neurologic outcome in patients following cardiac arrest should we be hot to cool off our patients Teresa L Smith1 and Thomas P Bleck2 1 Fellow Neuroscience Critical Care and Clinical Instructor of Neurology University of Virginia School of Medicine Charlottesville Virginia USA 2Head Division of Neurocritical Care Director Nerancy Neuroscience Intensive Care Unit and Professor of Neurology Neurosurgery and Medicine University of Virginia School of Medicine Charlottesville Virginia USA Correspondence Teresa L Smith tls2u@ Published online 16 August 2002 Critical Care 2002 6 377-380 This article is online at http content 6 5 377 2002 BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Hypothermia as a protectant of neurologic function in the treatment of cardiac arrest patients although not a new concept is now supported by two recent randomized prospective clinical trials. The basic science research in support of the effects of hypothermia at the cellular and animal levels is extensive. The process of cooling for cerebral protection holds potential promise for human resuscitation efforts in multiple realms. It appears that at least those patients who suffer a witnessed cardiac arrest with ventricular fibrillation and early restoration of spontaneous circulation such as those who were included in the European and Australian trials discussed here should be considered for hypothermic therapy. Keywords cardiac arrest cerebral protection cooling hypothermia resuscitation In two recent issues of New England Journal of Medicine studies using hypothermia in patients following cardiac arrest CA to improve neurologic outcome were presented and debated 1-8 . Not a new issue having first surfaced in the 1950s 9 10 hypothermia as a treatment strategy is potentially promising as a mechanism to curtail neurologic injury in specific although not fully defined .