tailieunhanh - Báo cáo khoa học: "Anaplasma phagocytophilum infection in a domestic cat in Finland: Case report"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Anaplasma phagocytophilum infection in a domestic cat in Finland: Case report. | Heikkilă et al. Acta Veterinaria Scandinavian 2010 52 62 http content 52 1 62 AVS ACTAVETERINARIA SCANDINAVICA CASE REPORT Open Access Anaplasma phagocytophilum infection in a domestic cat in Finland Case report I I II ft A I I -I I I 1 A rt I I 2 A I ft 1 1 II 2 I . nr- 2 -1-1 - -II 1 Helka M Heikkila Anna Bondarenko Andrea Mihalkov Kurt Pfister Thomas Spillmann Abstract Background Anaplasmosis is a vectorborne disease caused by the gram-negative bacterium Anaplasma phagocytophilum. This species displays positive tropism to granulocytes and can cause illness in several mammalian species including cats dogs and humans. It is considered as an emerging disease in Europe. The clinical signs are nonspecific and include fever lethargy and inappetence. The most typical hematologic abnormality is thrombocytopenia. A tentative diagnosis can be made by detecting intracytoplasmic morulae inside neutrophils. The diagnosis is confirmed by PCR and serology in paired serum samples. A sample for PCR analysis should be taken before treatment. Anaplasmosis is treated with doxycycline. Case presentation A feline case of anaplasmosis is presented. The history clinical presentation diagnostics treatment and follow-up are discussed. Conclusions This case indicates that Anaplasma phagocytophilum infects cats in Finland. To provide accurate treatment anaplasmosis should be listed as a differential diagnosis in cats suffering from acute febrile illness with previous tick exposure. Background Anaplasmosis is a vectorborne disease caused by the gram-negative bacterium Anaplasma phagocytophilum encompassing the former Ehrlichia phagocytophila Ehrlichia equi and the human granulocytic ehrlichiosis agent 1 . Although anaplasmosis has been known for decades as a tickborne fever affecting domestic ruminants in Europe 2 A. phagocytophilum can also infect several other mammalian species including dogs 3 horses 4 cats 5 small rodents 6 cervids 6-9 European bison 2 wild boars .