tailieunhanh - Báo cáo y học: " The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis. | Respiratory Research BioMed Central Research Open Access The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis Virginie Barbarin1 Aurélie Nihoul1 Pierre Misson1 Mohammed Arras1 Monique Delos2 Isabelle Leclercq3 Dominique Lison1 and Francois Huaux 1 Address 1Industrial Toxicology and Occupational Medicine Unit Faculty of Medicine Université catholique de Louvain Clos Chapelle-aux-champs 1200 Brussels Belgium - Laboratory of Pathology University Hospital of Mont Godinne Université catholique de Louvain Avenue Dr. G. Thérasse 1 5530 Yvoir Belgium and 3Unit of Gastro-enterology Faculty of Medicine Université catholique de Louvain 53-79 Avenue E. Mounier 53 1200 Brussels Belgium Email Virginie Barbarin - Aurélie Nihoul - anihoul@ Pierre Misson - Mohammed Arras - arras@ Monique Delos - Isabelle Leclercq - Dominique Lison - lison@ Francois Huaux - huaux@ Corresponding author Published 07 October 2005 Received 07 April 2005 Respiratory Research 2005 6 112 doi 1465-9921-6-112 Accepted 07 October 2005 This article is available from http content 6 1 1 12 2005 Barbarin et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background It has been generally well accepted that chronic inflammation is a necessary component of lung fibrosis but this concept has recently been challenged. Methods Using biochemical histological immunohistochemistry and cellular analyses we compared the lung responses inflammation and fibrosis to fibrogenic silica particles and 25 mg g lung in .

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