tailieunhanh - Báo cáo y học: "Effects of nano particles on antigen-related airway inflammation in mice"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Effects of nano particles on antigen-related airway inflammation in mice. | Respiratory Research BioMed Central Research Open Access Effects of nano particles on antigen-related airway inflammation in mice Ken-ichiro Inoue1 Hirohisa Takano 1 2 Rie Yanagisawa1 Miho Sakurai1 Takamichi Ichinose3 Kaori Sadakane3 and Toshikazu Yoshikawa2 Address Unhalation Toxicology and Pathophysiology Research Team National Institute for Environmental Studies Tsukuba Ibaraki Japan 2Inflammation and Immunology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kyoto Japan and 3Department of Health Science Oita University of Nursing and Health Science Oita Japan Email Ken-ichiro Inoue - Hirohisa Takano - htakano@ Rie Yanagisawa - yanagi@ Miho Sakurai - Takamichi Ichinose - ichinose@ Kaori Sadakane - sadakane@ Toshikazu Yoshikawa - toshi@ Corresponding author Published 16 September 2005 Respiratory Research 2005 6 106 doi 1465-9921-6-106 Received 28 January 2005 Accepted 16 September 2005 This article is available from http content 6 1 106 2005 Inoue et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Particulate matter PM can exacerbate allergic airway diseases. Although health effects of PM with a diameter of less than 100 nm have been focused few studies have elucidated the correlation between the sizes of particles and aggravation of allergic diseases. We investigated the effects of nano particles with a diameter of 14 nm or 56 nm on antigen-related airway inflammation. Methods ICR mice were divided into six experimental groups. Vehicle two sizes of carbon nano particles ovalbumin OVA and OVA nano particles were administered