tailieunhanh - Báo cáo y học: " Impediment in upper airway stabilizing forces assessed by phrenic nerve stimulation in sleep apnea patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Impediment in upper airway stabilizing forces assessed by phrenic nerve stimulation in sleep apnea patients. | Respiratory Research BioMed Central Research Open Access Impediment in upper airway stabilizing forces assessed by phrenic nerve stimulation in sleep apnea patients F Sériès 1 2 E Vérin1 2 3 and T Similowski2 4 Address 1Centre de recherche Hôpital Laval Institut universitaire de cardiologie et de pneumologie de 1 Université Laval Quebec City Quebec Canada 2UPRES EA 2397 Université Paris VI Pierre et Marie Curie Paris France 3Service de Physiologie GRHV EA 3830 Université de Rouen Rouen France and 4Service de Pneumologie Groupe Hospitalier Pitié-Salpêtrière Assistance Publique - Hôpitaux de Paris Paris France Email F Sériès - E Vérin - everin@ T Similowski - Corresponding author Published 07 September 2005 Received 29 June 2005 Respiratory Research 2005 6 99 doi 1465-9921 -6-99 Accepted 07 September 2005 This article is available from http content 6 1 99 2005 Sériès et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The forces developed during inspiration play a key role in determining upper airway stability and the occurrence of nocturnal breathing disorders. Phrenic nerve stimulation applied during wakefulness is a unique tool to assess Upper airway dynamic properties and to measure the overall mechanical effects of the inspiratory process on UA stability. Objectives To compare the flow pressure responses to inspiratory and expiratory twitches between sleep apnea subjects and normal subjects. Methods Inspiratory and expiratory twitches using magnetic nerve stimulation completed in eleven untreated sleep apnea subjects and ten normal subjects. Results In both groups higher flow and pressure were