tailieunhanh - Báo cáo khoa học: "Changes in thermal nociceptive responses in dairy cows following experimentally induced Escherichia coli mastitis"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Changes in thermal nociceptive responses in dairy cows following experimentally induced Escherichia coli mastitis. | Rasmussen et al. Acta Veterinaria Scandinavica 2011 53 32 http content 53 1 32 AVS ACTAVETERINARIA Scolidmov cc ia SCANDINAVICA RESEARCH Open Access Changes in thermal nociceptive responses in dairy cows following experimentally induced Escherichia coli mastitis Ditte B Rasmussen1 Katrine Fogsgaard2 Christine M R0ntved2 Ilka C Klaas3 and Mette S Herskin2 Abstract Background Mastitis is a high incidence disease in dairy cows. The acute stage is considered painful and inflammation can lead to hyperalgesia and thereby contribute to decreased welfare. The aim of this study was to examine changes in nociceptive responses toward cutaneous nociceptive laser stimulation NLS in dairy cows with experimentally induced Escherichia coli mastitis and correlate behavioral changes in nociceptive responses to clinical and paraclinical variables. Methods Seven Danish Holstein-Friesian cows were kept in tie-stalls where the E. coli associated mastitis was induced and laser stimulations were conducted. Measurements of rectal temperature somatic cell counts white blood cell counts and E. coli counts were conducted. Furthermore scores were given for anorexia local udder inflammation and milk appearance to quantify the local and systemic disease response. In order to quantify the nociceptive threshold behavioral responses toward cutaneous NLS applied to six skin areas at the tarsus metatarsus and udder hind quarters were registered at evening milking on day 0 control and days 1 2 3 6 and 10 after experimental induction of mastitis. Results All clinical and paraclinical variables were affected by the induced mastitis. All cows were clinically ill on days 1 and 2. The cows responded behaviorally toward the NLS. For hind leg stimulation the proportion of cows responding by stepping was higher on day 0 than days 3 and 6 and the frequency of leg movements after laser stimulation tended to decrease on day 1 compared to the other days. After udder stimulation the proportion