tailieunhanh - Báo cáo y học: "Fractal ventilation enhances respiratory sinus arrhythmia"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Fractal ventilation enhances respiratory sinus arrhythmia. | Respiratory Research BioMed Central Research Open Access Fractal ventilation enhances respiratory sinus arrhythmia W Alan C Mutch 1 M Ruth Graham1 Linda G Girling1 and John F Brewster2 Address Department of Anesthesia Faculty of Medicine Anesthesia Research Laboratory University of Manitoba Winnipeg MB Canada and 2Department of Statistics Faculty of Science University of Manitoba Winnipeg MB Canada Email W Alan C Mutch - amutch@ M Ruth Graham - mrgraha@ Linda G Girling - girling1@ John F Brewster - john_brewster@ Corresponding author Published 09 May 2005 Received 31 January 2005 Respiratory Research 2005 6 41 doi 1465-9921 -6-41 Accepted 09 May 2005 This article is available from http content 6 1 41 2005 Mutch et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Programming a mechanical ventilator with a biologically variable or fractal breathing pattern an example of 1 f noise improves gas exchange and respiratory mechanics. Here we show that fractal ventilation increases respiratory sinus arrhythmia RSA - a mechanism known to improve ventilation perfusion matching. Methods Pigs were anaesthetised with propofol ketamine paralysed with doxacurium and ventilated in either control mode CV or in fractal mode FV at baseline and then following infusion of oleic acid to result in lung injury. Results Mean RSA and mean positive RSA were nearly double with FV both at baseline and following oleic acid. At baseline mean RSA msec with CV and msec with FV n 10 p post oleic acid mean RSA msec with CV and msec with FV n 9 p at baseline mean positive RSA msec with CV and msec with FV p .