tailieunhanh - Báo cáo khoa học: "Proton nuclear magnetic resonance spectroscopy based investigation on propylene glycol toxicosis in a Holstein cow"

Acta Veterinaria Scandinavica Research Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Proton nuclear magnetic resonance spectroscopy based investigation on propylene glycol toxicosis in a Holstein cow. | Acta Veterinaria Scandinavica BioMed Central Open Access Proton nuclear magnetic resonance spectroscopy based investigation on propylene glycol toxicosis in a Holstein cow Hanne Christine Bertram 1 Bent Ole Petersen2 Jens 0 Duus2 Mogens Larsen3 Birgitte-Marie L Raun3 and Niels Bastian Kristensen3 Address Department of Food Science Faculty of Agricultural Sciences Aarhus University . Box 102 DK-5792 Ẳrslev Denmark 2Carlsberg Laboratory Gamle Carlsberg Vej 10 DK-2500 Valby Denmark and 3Department of Animal Health Welfare and Nutrition Faculty of Agricultural Sciences Aarhus University . Box 50 DK-8830 Tjele Denmark Email Hanne Christine Bertram - Bent Ole Petersen - bp@ Jens 0 Duus - jd@ Mogens Larsen - Birgitte-Marie LRaun - Niels Bastian Kristensen - Corresponding author Published 13 June 2009 Received 19 March 2009 Acta Veterinaria Scandinavica 2009 51 25 doi 1751-0147-51 -25 Accepted 13 June 2009 This article is available from http content 51 1 25 2009 Bertram et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background It is unknown which metabolites are responsible for propylene glycol PG -induced toxicosis and a better understanding of the underlying mechanisms explaining incidences of abnormal behaviour of dairy cows fed PG is therefore needed. Methods The study included three cows of which one developed PG toxicosis. In order to investigate how the metabolism of PG differed in the cow developing toxicosis proton nuclear magnetic resonance NMR spectroscopy was applied on ruminal fluids and blood plasma samples obtained before and after feeding with PG. .