tailieunhanh - Báo cáo y học: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment. | Respiratory Research BioMed Central Research Open Access Alveolar macrophage-epithelial cell interaction following exposure to atmospheric particles induces the release of mediators involved in monocyte mobilization and recruitment Hiroshi Ishii 1 2 Shizu Hayashi1 James C Hogg1 Takeshi Fujii2 Yukinobu Goto1 Noriho Sakamoto1 Hiroshi Mukae2 Renaud Vincent13 and Stephan F van Eeden 1 Address 1James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research St. Paul s Hospital University of British Columbia 1081 Burrard Street Vancouver BC V6Z 1Y6 Canada 2Second Department of Internal medicine Nagasaki University School of Medicine Nagasaki Japan and Environmental Health Directorate Health Canada Ottawa Ontario Canada Email Hiroshi Ishii - hishii2@ Shizu Hayashi - SHayashi@ James C Hogg - JHogg@ Takeshi Fujii - tmks@ Yukinobu Goto - ygoto@ Noriho Sakamoto - NSakamoto@ Hiroshi Mukae - hmukae@ Renaud Vincent - Renaud_vincent@ Stephan F van Eeden - SVaneeden@ Corresponding author fEqual contributors Published 01 August 2005 Respiratory Research 2005 6 87 doi 1465-9921 -6-87 Received 04 January 2005 Accepted 01 August 2005 This article is available from http content 6 1 87 2005 Ishii et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Studies from our laboratory have shown that human alveolar macrophages AM and bronchial epithelial cells HBEC exposed to ambient particles PM10 in vitro increase their production of inflammatory mediators and that supernatants from PM10-exposed cells shorten the transit time of monocytes through the bone marrow and promote their .