tailieunhanh - Báo cáo y học: " CD8+ T lymphocytes in lung tissue from patients with idiopathic pulmonary fibrosis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" CD8+ T lymphocytes in lung tissue from patients with idiopathic pulmonary fibrosis. | BioMed Central Respiratory Research Research Open Access CD8 T lymphocytes in lung tissue from patients with idiopathic pulmonary fibrosis Zoe Daniil1 Panagiota Kitsanta2 George Kapotsis1 Maria Mathioudaki2 Androniki Kollintza1 Marilena Karatza3 Joseph Milic-Emili4 Charis Roussos1 and Spyros A Papiris 1 Address Department of Critical Care and Pulmonary Services National and Capodistrian University of Athens Evangelismos Hospital Athens Greece 2Pathology Department Evangelismos Hospital Athens Greece 3Hematology Department Evangelismos Hospital Athens Greece and 4Meakins-Cristie Laboratories McGill University Montreal Quebec Canada Email Zoe Daniil - zdaniil@ Panagiota Kitsanta - George Kapotsis - gkapotsis@ Maria Mathioudaki - mmathioudaki@ Androniki Kollintza - akollin@ Marilena Karatza - mkaratza@ Joseph Milic-Emili - Charis Roussos - Croussos@ Spyros A Papiris - papiris@ Corresponding author Published 24 July 2005 Received 26 May 2005 Respiratory Research 2005 6 81 doi 1465-9921 -6-81 Accepted 24 July 2005 This article is available from http content 6 1 81 2005 Daniil et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Several studies have implicated a role of inflammation in the pathogenesis of lung damage in idiopathic pulmonary fibrosis IPF . Parenchymal lung damage leads to defects in mechanics and gas exchange and clinically manifests with exertional dyspnea. Investigations of inflammatory cells in IPF have shown that eosinophils neutrophils and CD8 TLs may be associated with worse prognosis. We wished to investigate by quantitative .