tailieunhanh - Báo cáo khoa học: "Concentrations of cardiac Troponin I before and after ovariohysterectomy in 46 female dogs with pyometra"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Concentrations of cardiac Troponin I before and after ovariohysterectomy in 46 female dogs with pyometra. | Acta Veterinaria Scandinavica BioMed Central Open Access Concentrations of cardiac Troponin I before and after ovariohysterectomy in 46 female dogs with pyometra Lena Pelander 1 2 Ragnvi Hagman2 and Jens Haggstrom2 Address University Teaching Hospital Swedish University of Agricultural Science Uppsala Sweden and 2Department of Clinical Sciences Swedish University of Agricultural Science Uppsala Sweden Email Lena Pelander - Ragnvi Hagman - Jens Haggstrom - Corresponding author Published II September 2008 Received 17 March 2008 .J Accepted 11 September 2008 Acta Veterinaria Scandinavica 2008 50 35 doi 1751-0147-50-35 This article is available from http content 50 1 35 2008 Pelander et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Canine pyometra is a common disease in countries where routine spaying of young dogs is not common practice. This disease is known to lead to systemic inflammation potentially affecting multiple organs in the body including the heart. Cardiac-specific Troponin I cTnI is a sensitive marker of myocardial cell damage which can result from ischemia trauma toxins or inflammation. Dogs with pyometra are also exposed to anaesthesia which can potentially result in myocardial cell damage. The aims of the study were 1 to evaluate the occurrence of myocardial cell damage as indicated by increased serum concentrations of cTnI in dogs with pyometra and relate these to presence of systemic inflammation and 2 to evaluate the change in cTnI-concentrations after anaesthesia and surgery. Methods Serum cTnI concentration was measured preoperatively and one day after surgery in 46 female dogs .