tailieunhanh - Báo cáo y học: "Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A. | Respiratory Research BioMed Central Research Open Access Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A Heinz Fehrenbach 2 Sebastian Tews1 Antonia Fehrenbach1 2 Matthias Ochs1 4 Thorsten Wittwer3 Thorsten Wahlers3 and Joachim Richter1 Address 1Division of Electron Microscopy Centre of Anatomy University of Gottingen Kreuzbergring 36 D-37075 Gottingen Germany 2Clinical Research Group Chronic Airway Diseases Department of Internal Medicine Respiratory Medicine Philipps-University Baldingerstrasse D-35043 Marburg Germany 3Department of Cardiothoracic and Vascular Surgery Friedrich Schiller University Jena Bachstrasse 18 D-07740 Jena Germany and 4Institute of Anatomy University of Bern Baltzerstrasse 2 CH-3000 Bern 9 Switzerland Email Heinz Fehrenbach - fehrenba@ Sebastian Tews - Antonia Fehrenbach - fehrenb2@ Matthias Ochs - ochs@ Thorsten Wittwer - Thorsten Wahlers - Joachim Richter - jrichte@ Corresponding author Published 21 June 2005 Received 09 August 2004 Respiratory Research 2005 6 60 doi l465-992l-6-60 Accepted 21 June 2005 This article is available from http content 6 l 60 2005 Fehrenbach et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Declining levels of surfactant protein A SP-A after lung transplantation are suggested to indicate progression of ischemia reperfusion IR injury. We hypothesized that the previously described preservation-dependent improvement of alveolar surfactant integrity after IR was associated with alterations in intraalveolar SP-A levels. Methods .