tailieunhanh - Báo cáo y học: "Acute febrile neutrophilic dermatosis (Sweet’s syndrome) in a child, associated with a rotavirus infection: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Acute febrile neutrophilic dermatosis (Sweet’s syndrome) in a child, associated with a rotavirus infection: a case report. | Makis et al. Journal of Medical Case Reports 2010 4 281 http content 4 1 281 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Acute febrile neutrophilic dermatosis Sweet s syndrome in a child associated with a rotavirus infection a case report 1 1 1 7-2 1 3 Alexandros Makis Stavros Stavrou Nikolaos Chaliasos Aikaterini Zioga Antonios P Vlahos Georgios Gaitanis Antigone Siamopoulou 1 Ioannis D Bassukas3 Abstract Introduction Sweet s syndrome characterized by fever blood neutrophilia and inflammatory skin lesions is rarely diagnosed in children. It presents in three clinical settings classical Sweet s syndrome usually after a respiratory tract infection malignancy-associated frequently related to acute myelogeneous leukemia and drug-induced. We present to the best of our knowledge the first case of a rotavirus -infection-related Sweet s syndrome. Case presentation An 18-month-old boy of Hellenic origin was referred to us with diarrhea fever neutrophilia typical skin lesions asymmetrical hip arthritis and oropharyngeal involvement. A skin biopsy confirmed the diagnosis. Thorough screening did not reveal any underlying systemic illness except for the confirmation of an overt rotavirus infection. The syndrome responded promptly upon corticosteroid administration no recurrence was observed. Conclusion Besides describing the connection of Sweet s syndrome to a rotavirus infection this case report is also a reminder that in a child presenting with a febrile papulo-nodular rash with neutrophilia Sweet s syndrome should be included in the differential. Introduction Sweet s syndrome acute febrile neutrophilic dermatosis is characterized by a constellation of clinical symptoms and physical findings which include fever blood and tissue neutrophilia leading to the development of tender erythematous inflammatory skin lesions papules nodules plaques histopathologically characterized by the presence of abundant mature neutrophils 1 . It .

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