tailieunhanh - Báo cáo y học: " Mycotic aneurysm of the inferior gluteal artery caused by non-typhi Salmonella in a man infected with HIV: a case report."

Tham khảo luận văn - đề án 'báo cáo y học: " mycotic aneurysm of the inferior gluteal artery caused by non-typhi salmonella in a man infected with hiv: a case report."', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | Fielder et al. Journal of Medical Case Reports 2010 4 273 http content 4 1 273 jAc JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Mycotic aneurysm of the inferior gluteal artery caused by non-typhi Salmonella in a man infected with HIV a case report Jon Fielder1 Kenneth Miriti2 Peter Bird3 Abstract Introduction Non-typhi Salmonellae infections represent major opportunistic pathogens affecting human immunodeficiency virus-infected individuals residing in sub-Saharan Africa. To the best of our knowledge we report the first documented case in the medical literature of a Salmonella-induced mycotic aneurysm involving an artery supplying the gluteal region. Case presentation A 37-year-old black Kenyan man infected with human immunodeficiency virus with a CD4 count of 132 cells per microliter presented with a pulsatile gluteal mass and debilitating pain progressing over one week. He was receiving prophylaxis with trimethoprim-sulfamethoxazole. Aspiration of the mass yielded gross blood. An ultrasound examination revealed a 37 ml vascular structure with an intra-luminal clot. Upon exploration a true aneurysm of the inferior gluteal artery was identified and successfully resected. A culture of the aspirate grew a non-typhi Salmonellae species. Following resection he was treated with oral ciprofloxacin for 10 weeks. He later began anti-retroviral therapy. Forty-two months after the initial diagnosis he remained alive and well. Conclusions Clinicians caring for patients infected with human immunodeficiency virus in Africa and other resource-limited settings should be aware of the invasive nature of Salmonella infections and the potential for aneurysm formation in unlikely anatomical locations. Rapid initiation of appropriate anti-microbial chemotherapy and surgical referral is needed. Use of trimethoprim-sulfamethoxazole prophylaxis does not routinely prevent invasive Salmonella infections. Introduction Non-typhi Salmonellae NTS .