tailieunhanh - Báo cáo y học: "Cyclosporine-A therapy-induced multiple bilateral breast and accessory axillary breast fibroadenomas: a case report"

Tham khảo luận văn - đề án 'báo cáo y học: "cyclosporine-a therapy-induced multiple bilateral breast and accessory axillary breast fibroadenomas: a case report"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả | Darwish et al. Journal of Medical Case Reports 2010 4 267 http content 4 1 267 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Cyclosporine-A therapy-induced multiple bilateral breast and accessory axillary breast fibroadenomas a case report Ahmed Darwish 1 Ayman O Nasr1 Lamya A El Hassan2 Ahmed H Fahal1 Abstract Introduction Breast adenoma is common. However in the setting of post-transplantation immune suppression it may be expressed differently. Case presentation A 35-year-old Sudanese woman with a history of renal transplantation two and half years prior to presentation was on a single immune suppression therapy in the form of cyclosporine-A since the transplantation. During a regular follow-up visit she was noticed to have gingival hypertrophy and bilateral breast and axillary swellings. She underwent successful surgical resection of the bilateral fibroadenomas. Conclusions Cyclosporine-A therapy post renal transplantation is associated with an increased incidence of benign breast changes as fibroadenoma. Regular follow-up and appropriate selection of immunosuppressant therapy are essential in the post transplantation management of these patients. Introduction The presence of bilateral breast fibroadenoma is rare. To the best of our knowledge there are no previous reports of bilateral breast fibroadenoma associated with accessory axillary breast fibroadenoma in the English medical literature. We present the case of a woman with bilateral breast fibroadenoma secondary to cyclosporine-A therapy post renal transplantation. Case presentation A 35-year-old Sudanese woman presented to the Surgical Out-patient Department at Soba University Hospital Khartoum Sudan with bilateral breast and axillary swellings. Her condition started one year prior to presentation with a small painless right breast lump slowly increasing in size. It was not considered necessary by our patient to report it during her regular follow-up until seven