tailieunhanh - Báo cáo y học: "Ventilator-associated pneumonia in a surgical intensive care unit: epidemiology, etiology and comparison of three bronchoscopic methods for microbiological specimen sampling"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Ventilator-associated pneumonia in a surgical intensive care unit: epidemiology, etiology and comparison of three bronchoscopic methods for microbiological specimen sampling. | Available online http content 5 3 167 Primary research Ventilator-associated pneumonia in a surgical intensive care unit epidemiology etiology and comparison of three bronchoscopic methods for microbiological specimen sampling Hans-Jurgen Woske Thomas Roding Ines Schulz and Hartmut Lode Hospital Ernst von Bergmann Potsdam Germany City Hospital Zehlendorf Berlin Germany Correspondence H-J Woske Department of Anaesthesiology and Intensive Care Medicine Hospital Ernst von Bergmann Charlottenstrasse 72 14467 Potsdam Germany. Tel. 49 331 2415034 fax 49 331 2415030 e-mail Received 5 October 2000 Revisions requested 4 December 2000 Revisions received 15 December 2000 Accepted 26 December 2000 Published 27 April 2001 Critical Care 2001 5 167-173 2001 Woske et al licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Background Ventilator-associated bacterial pneumonia VAP is a important intensive care unit ICU -acquired infection in mechanically ventilated patients. Early and correct diagnosis of VAP is difficult but is an urgent challenge for an optimal antibiotic treatment. The aim of the study was to evaluate the incidence and microbiology of ventilator-associated pneumonia and to compare three quantitative bronchoscopic methods for diagnosis. Methods A prospective open epidemiological clinical study was performed in a surgical ICU. In a prospective study 279 patients admitted to a 14-bed surgical ICU during a 1-year period were evaluated with regard to VAP. Three quantitative culture bronchoscopic techniques for identifying the etiological agent were compared bronchoalveolar lavage BAL protected specimen brush PSB and bronchoscopic tracheobronchial secretion TBS . Results Among 103 long-term ventilated patients 49 48 developed one or more VAPs a total of 60 VAPs . The incidence was 24 VAPs per 100 ventilated patients or 23 VAPs per 1000 ventilator days. BAL PSB and TBS with quantitative measurements .