tailieunhanh - Báo cáo khoa hoc:" Simultaneous measurements of kinematics and fMRI: compatibility assessment and case report on recovery evaluation of one stroke patient"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Simultaneous measurements of kinematics and fMRI: compatibility assessment and case report on recovery evaluation of one stroke patient | Casellato et al. Journal of NeuroEngineering and Rehabilitation 2010 7 49 http content 7 1 49 IHli JOURNAL OF NEUROENGINEERING NCR AND REHABILITATION RESEARCH Open Access Simultaneous measurements of kinematics and fMRI compatibility assessment and case report on recovery evaluation of one stroke patient 111 1 12 Claudia Casellato Simona Ferrante Marta Gandolla Nicola Volonterio Giancarlo Ferrigno Giuseppe Baselli Ti 7ÍTỉ n 1 p r 2 f f i n i3 Ạ I Hcirl r i K l orfcirT Tin 3 K ir Jfor ii4 A Iocco rTj DoHrr tr f hi 1 Tiziano Fiattini Albeito Maitegani Franco Molteni Alessandra Pediocciii Abstract Background Correlating the features of the actual executed movement with the associated cortical activations can enhance the reliability of the functional Magnetic Resonance Imaging fMRI data interpretation. This is crucial for longitudinal evaluation of motor recovery in neurological patients and for investigating detailed mutual interactions between activation maps and movement parameters. Therefore we have explored a new set-up combining fMRI with an optoelectronic motion capture system which provides a multi-parameter quantification of the performed motor task. Methods The cameras of the motion system were mounted inside the MR room and passive markers were placed on the subject skin without any risk or encumbrance. The versatile set-up allows 3-dimensional multi-segment acquisitions including recording of possible mirror movements and it guarantees a high inter-sessions repeatability. We demonstrated the integrated set-up reliability through compatibility tests. Then an fMRI block-design protocol combined with kinematic recordings was tested on a healthy volunteer performing finger tapping and ankle dorsal- plantar-flexion. A preliminary assessment of clinical applicability and perspectives was carried out by pre- and post rehabilitation acquisitions on a hemiparetic patient performing ankle dorsal- plantar-flexion. For all sessions the proposed .