tailieunhanh - Báo cáo y học: " The Beijing genotype and drug resistant tuberculosis in the Aral Sea region of Central Asia"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:The Beijing genotype and drug resistant tuberculosis in the Aral Sea region of Central Asia. | Respiratory Research BioMed Central Research Open Access The Beijing genotype and drug resistant tuberculosis in the Aral Sea region of Central Asia Helen Suzanne Cox1 Tanja Kubica2 Daribay Doshetov3 Yared Kebede4 Sabine Rusch-Gerdess2 and Stefan Niemann 2 Address 1Médecins Sans Frontieres MSF Aral Sea Area Programme Uzbekistan and Turkmenistan Tashkent Uzbekistan 2National Reference Center for Mycobacteria Forschungszentrum Borstel Borstel Germany 3Ministry of Health Nukus Karakalpakstan Uzbekistan and 4Médecins Sans Frontieres MSF Amsterdam Holland Email Helen Suzanne Cox - Tanja Kubica - tkubica@ Daribay Doshetov - rtc@ Yared Kebede - Sabine Rusch-Gerdess - srueschg@ Stefan Niemann - sniemann@ Corresponding author Published 08 November 2005 Received 25 August 2005 Accepted 08 November 2005 Respiratory Research 2005 6 134 doi 1465-9921-6-1 34 This article is available from http content 6 1 1 34 2005 Cox et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background After the collapse of the Soviet Union dramatically increasing rates of tuberculosis and multidrug-resistant tuberculosis MDR-TB have been reported from several countries. This development has been mainly attributed to the widespread breakdown of TB control systems and declining socio-economic status. However recent studies have raised concern that the Beijing genotype of Mycobacterium tuberculosis might be contributing to the epidemic through its widespread presence and potentially enhanced ability to acquire resistance. Methods A total of 397 M. tuberculosis strains from a cross sectional survey performed in the Aral