tailieunhanh - Báo cáo y học: "Regulatory role of CD8+ T lymphocytes in bone marrow eosinophilopoiesis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:Regulatory role of CD8+ T lymphocytes in bone marrow eosinophilopoiesis. | Respiratory Research BioMed Central Research Regulatory role of CD8 T lymphocytes in bone marrow eosinophilopoiesis Madeleine Râdinger 11 Svetlana Sergejeva11 2 Anna-Karin Johansson1 Carina Malmhall1 Apostolos Bossios1 Margareta Sjostrand1 James J Lee3 and Jan Lotvall1 Open Access Address 1Lung Pharmacology Group Department of Internal Medicine Respiratory Medicine and Allergology Goteborg University Goteborg Sweden 2The Unit for Lung Investigations Faculty of Science Department of Gene Technology Tallinn University of Technology Estonia and 3Divison of Pulmonary Medicine Mayo Clinic Scottsdale AZ 85259 USA Email Madeleine Râdinger - Svetlana Sergejeva - Anna- Karin Johansson - Carina Malmhall - Apostolos Bossios - Margareta Sjostrand - James J Lee - jjlee@ Jan Lotvall - Corresponding author fEqual contributors Published 01 June 2006 Respiratory Research 2006 7 83 doi l465-992l-7-83 Received ll March 2006 Accepted 0l June 2006 This article is available from http content 7 l 83 2006 Rảdinger et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background There is a growing body of evidence to suggest that CD8 T lymphocytes contribute to local allergen-induced eosinophilic inflammation. Since bone marrow BM responses are intricately involved in the induction of airway eosinophilia we hypothesized that CD8 T lymphocytes as well as CD4 T lymphocytes may be involved in this process. Methods Several approaches were utilized. Firstly mice overexpressing .