tailieunhanh - Báo cáo y học: " Health status measurement in COPD: the minimal clinically important difference of the clinical COPD questionnaire"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Health status measurement in COPD: the minimal clinically important difference of the clinical COPD questionnaire. | Respiratory Research BioMed Central Research Open Access Health status measurement in COPD the minimal clinically important difference of the clinical COPD questionnaire JWH Kocks1 MG Tuinenga1 SM Uil2 JWK van den Berg2 E Stâhl3 4 and T van der Molen 1 4 Address Department of General Practice University Medical Center Groningen The Netherlands 2Department of Pulmonary Diseases Isala klinieken Zwolle The Netherlands 3AstraZeneca R D Lund Sweden and 4Primary Care Respiratory Medicine University of Aberdeen UK Email JWH Kocks - MG Tuinenga - SM Uil - JWK van den Berg - E Stâhl - T van der Molen - Corresponding author Published 07 April 2006 Received 11 October 2005 Respiratory Research 2006 7 62 doi 1465-9921 -7-62 Accepted 07 April 2006 This article is available from http content 7 1 62 2006 Kocks et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Patient-reported outcomes PRO questionnaires are being increasingly used in COPD clinical studies. The challenge facing investigators is to determine what change is significant ie what is the minimal clinically important difference MCID . This study aimed to identify the MCID for the clinical COPD questionnaire CCQ in terms of patient referencing criterion referencing and by the standard error of measurement SEM . Methods Patients were 40 years of age diagnosed with COPD had a smoking history of 10 pack-years and were participating in a randomized controlled clinical trial comparing intravenous and oral prednisolone in patients admitted with an acute exacerbation of COPD. The