tailieunhanh - Báo cáo y học: "Hormonal regulation of alveolarization: structure-function correlation"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Hormonal regulation of alveolarization: structure-function correlation. | BioMed Central Respiratory Research Research Open Access Hormonal regulation of alveolarization structure-function correlation Samuel J Garbed1 Huayan Zhang11 Joseph P Foley1 Hengjiang Zhao1 Stephan J Butler1 Rodolfo I Godinez2 Marye H Godinez2 Andrew J Gow1 and Rashmin C Savani 3 Address 1Division of Neonatology Department of Pediatrics Children s Hospital of Philadelphia University of Pennsylvania School of Medicine Philadelphia PA USA 2Department of Anesthesiology and Critical Care Medicine Children s Hospital of Philadelphia University of Pennsylvania School of Medicine Philadelphia PA USA and 3Division of Neonatal-Perinatal Medicine Division of Pulmonary and Vascular Biology Room University of Texas Southwestern at Dallas Dallas TX USA Email Samuel J Garber - garbers@ Huayan Zhang - zhangh@ Joseph P Foley - jpfoley401@ Hengjiang Zhao - Stephan J Butler - BUTLERS@ Rodolfo I Godinez - GODINEZ@ Marye H Godinez - GODINEZM@ Andrew J Gow - GOW@ Rashmin C Savani - Corresponding author tEqual contributors Published 27 March 2006 Received 27 May 2005 Respiratory Research2006 7 47 doi 1465-9921-7-47 Accepted 27 March 2006 This article is available from http content 7 1 47 2006Garber et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Dexamethasone Dex limits and all-trans-retinoic acid RA promotes alveolarization. While structural changes resulting from such hormonal exposures are known their functional consequences are unclear. Methods Neonatal rats were treated with Dex and or RA during the first two weeks of life or

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