tailieunhanh - Báo cáo y học: "Marked disability and high use of nonsteroidal antiinflammatory drugs associated with knee osteoarthritis in rural China: a cross-sectional population-based survey"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Marked disability and high use of nonsteroidal antiinflammatory drugs associated with knee osteoarthritis in rural China: a cross-sectional population-based survey. | Ling et al. Arthritis Research Therapy 2010 12 R225 http content 12 6 R225 RESEARCH ARTICLE Open Access Marked disability and high use of nonsteroidal antiinflammatory drugs associated with knee osteoarthritis in rural China a cross-sectional population-based survey 1 2 3 1 1 1 71 4 5 Jianhao Ling Marlene Fransen Xiaozheng Kang Hu Li Yan Ke Zhiqiang Wang Yuqing Zhang Steve Su Abstract Introduction The burden of disability analgesia and health services use associated with knee pain and osteoarthritis OA in developing countries is relatively unknown despite a high proportion of these populations required to be engaged in heavy occupational physical activity throughout their life span. The aim of this survey was to estimate the burden of disability analgesia and health services use associated with knee pain in rural China. Methods This was a population-based cross-sectional survey among residents aged 50 years and older of Wuchuan County Inner Mongolia. Participants completed an interviewer-based questionnaire evaluating knee pain and associated disability analgesia and health services use and obtained bilateral standardized weight-bearing knee radiographs. Results Of the 1 027 participants 513 50 reported knee pain on most days of at least 1 month in the past year with 109 21 also demonstrating radiographic OA Kellgren-Lawrence grade 2 in the symptomatic knee. Adjusting for age gender body mass index BMI education and back pain the presence of knee pain was associated with significantly greater difficulty in walking climbing 10 steps stooping completing cleaning chores and preparing meals. Among the 513 subjects with knee pain the additional presence of radiographic evidence of OA was significantly associated with more occasions of unbearable pain 59 versus 36 and restricted activity 64 versus 39 as well as increased use of nonsteroidal antiinflammatory drugs NSAIDs 88 versus 78 and the reported number of doctor visits 59 versus 33 in the past