tailieunhanh - Báo cáo y học: "Increased frequency of metabolic syndrome among Vietnamese women with early rheumatoid arthritis: a cross-sectional study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Increased frequency of metabolic syndrome among Vietnamese women with early rheumatoid arthritis: a cross-sectional study. | Dao et al. Arthritis Research Therapy 2010 12 R218 http content 12 6 R218 RESEARCH ARTICLE Open Access Increased frequency of metabolic syndrome among Vietnamese women with early rheumatoid arthritis a cross-sectional study Hanh-Hung Dao1 2 Quan-Trung Do3 Junichi Sakamoto1 Abstract Introduction Rheumatoid arthritis RA is associated with increased morbidity and mortality due to cardiovascular disease and this occurs early in the disease process. The metabolic syndrome MetS may contribute to the excess cardiovascular burden observed in RA however little information is available regarding MetS in early RA. We aimed to identify the prevalence of MetS and to determine the potential factors associated with the presence of MetS in Vietnamese women with early RA. Methods A total of 105 consecutive women with early RA disease duration 3 years and 105 age-matched healthy women were checked for MetS according to six MetS definitions Joint Consensus International Diabetes Federation National Cholesterol Education Program 2004 and 2001 European Group for Study of Insulin Resistance and World Health Organization . Multivariate logistic regression models were constructed to determine independent predictors of MetS in women with RA. Results Prevalence of MetS varied from to according to the definitions used in women with RA and was higher P than in healthy controls from to . Among individual components of MetS differences between women with RA and controls were observed for hypertension P low high density lipoproteincholesterol HDL-C levels P and abdominal obesity P . After adjusting for age and physical activity higher erythrocyte sedimentation rate ESR odds ratios OR 95 confidence interval CI to P disease activity score DAS28 OR 95 CI to P health assessment questionnaire HAQ score OR 95 CI to P and less methotrexate use OR 95 CI .

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