tailieunhanh - Báo cáo y học: " Withdrawal of inhaled corticosteroids in people with COPD in primary care: a randomised controlled trial"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Withdrawal of inhaled corticosteroids in people with COPD in primary care: a randomised controlled trial. | Respiratory Research BioMed Central Research Withdrawal of inhaled corticosteroids in people with COPD in primary care a randomised controlled trial Aklak B Choudhury1 Carolyn M Dawson1 Hazel E Kilvington1 Sandra Eldridge1 Wai-Yee James1 Jadwiga A Wedzicha2 Gene S Feder1 and Chris J Griffiths 1 3 Address 1Centre for Health Sciences Queen Mary s School of Medicine and Dentistry Barts and The London 2 Newark Street London E1 2AT UK 2Academic Unit of Respiratory Medicine Royal Free and University College Medical School Hampstead Campus Rowland Hill Street Hampstead London NW3 2PF UK and 3MRC Asthma UK Centre in Allergic Mechanisms of Asthma 5th Floor Thomas Guy House Guy s Hospital London SE1 9RT UK Email Aklak B Choudhury - Carolyn M Dawson - tonydawson@ Hazel E Kilvington - HazelEK@ Sandra Eldridge - Wai-Yee James - waiyeewy@ Gene S Chris J Griffiths - Corresponding author Open Access Published 27 December 2007 Received 2 April 2007 Respiratory Research 2007 8 93 doi 1465-9921 -8-93 Accepted 27 December 2007 This article is available from http content 8 1 93 2007 Choudhury et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Guidelines recommend inhaled corticosteroids ICS for patients with severe chronic obstructive pulmonary disease COPD . Most COPD patients are managed in primary care and receive ICS long-term and irrespective of severity. The effect of withdrawing ICS from COPD patients in primary care is unknown. Methods In a pragmatic randomised double-blind placebo-controlled trial in 31