tailieunhanh - Báo cáo y học: " Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis. | BioMed Central Respiratory Research Research Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis Mrigank Srivastava1 Kathrin Steinwede1 Riku Kiviranta2 Jukka Morko2 Heinz-Gerd Hoymann3 Florian Langer4 Frank Buhling5 Tobias Welte1 and Ulrich A Maus 1 Address Department of Pulmonary Medicine Laboratory for Experimental Lung Research Hannover School of Medicine Hannover Germany 2Department of Medical Biochemistry and Molecular Biology University of Turku Turku Finland 3Division of Pre-clinical Airway Research Fraunhofer Institute of Toxicology and Experimental Medicine Hannover Germany 4Department of Pathology Hannover School of Medicine Hannover Germany and institute of Clinical Chemistry and Laboratory Diagnostics Carl-Thiem-Klinikum Cottbus Germany Email Mrigank Srivastava - Kathrin Steinwede - Riku Kiviranta - Riku_Kiviranta@ Jukka Morko - Heinz-Gerd Hoymann - Florian Langer - Frank Buhling - frank@ Tobias Welte - Ulrich A Maus - Corresponding author Open Access Published 18 July 2008 Received 16 January 2008 Respiratory Research 2008 9 54 doi 1465-9921 -9-54 Accepted 18 July 2008 This article is available from http content 9 1 54 2008 Srivastava et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Lung fibrosis is a devastating pulmonary disorder characterized by alveolar epithelial injury extracellular matrix deposition and scar tissue formation. .