tailieunhanh - Báo cáo khoa học: " Rapid Brain Cooling in Intubated Pigs through Nasal Flushing with Oxygen: Prevention of Brain Hyperthermia"

Tuyển tập các báo cáo nghiên cứu về bệnh thú y được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành thú y đề tài: Rapid Brain Cooling in Intubated Pigs through Nasal Flushing with Oxygen: Prevention of Brain Hyperthermia. | Acta vet. scand. 2001 42 459-464. Rapid Brain Cooling in Intubated Pigs through Nasal Flushing with Oxygen Prevention of Brain Hyperthermia By N. Einer-Jensen1 M. H. Khorooshi1 M. B. Petersen2 and P Svendsen1 1Dept. Physiology Pharmacology University of Southern Denmark and 2Dept. Neurosurgery Odense University Hospital Denmark. Einer-Jensen N Khorooshi MH Petersen MB Svendsen P Rapid brain cooling in intubated pigs through nasal flushing with oxygen Prevention of brain hyperthermia. Acta vet. scand. 2001 42 459-464. - Local cooling of the brain by the respiratory air is found in many animal species. The mechanism is based on cooling of the nasal vein blood and heat transfer in the cavernous sinus carotid artery complex and is therefore not active in anaesthetised intubated animals. The present experiment was made to investigate the effects of oxygen flushing of the nasal cavities in such animals. Nine anaesthetised intubated male pigs were used. The temperatures in the third ventricle and rectum were measured continuously. Oxygen was infused into the nasal cavities during 10 min periods interrupted by 10 min without flow. The nasal oxygen flow constantly induced a rapid reversible and flow dependant decrease in brain temperature C n 2 mean SD n at 4 l min C n 20 at 4-6 l min and C n 6 at 6 l min. The ventricle temperature decreased C n 8 when the animals were transferred to spontaneous respiration and the tracheal tube removed. It may be possible to protect the brain in intubated animals and humans from heat-induced damages by establishment of nasal flushing. carotid artery cavernous sinus rete mirabile. Introduction Many animal species have developed selective brain cooling mechanisms Bamford Eccles 1983 Elkhawad 1992 . Respiratory air cools the surface of the nasal cavities and thus nasal venous blood has a lower temperature than general body temperature. The blood may pass through a superficial or profound route v. .