tailieunhanh - Báo cáo khoa học: "15-Ketodihydro-PGF2α, Progesterone and Cortisol Profiles in Heifers after Induction of Parturition by Injection of Dexamethasone"

Tuyển tập các báo cáo nghiên cứu về bệnh thú y được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành thú y đề tài: 15-Ketodihydro-PGF2α, Progesterone and Cortisol Profiles in Heifers after Induction of Parturition by Injection of Dexamethasone. | Acta vet. scand. 2001 42 151-159. 15-Ketodihydro-PGF2a Progesterone and Cortisol Profiles in Heifers after Induction of Parturition by Injection of Dexamethasone By K. Konigsson1 K. Kask1 H. Gustafsson2 H. Kindahl1 and N. Parvizi3 department of Obstetrics and Gynaecology Centre for Reproductive Biology in Uppsala Swedish University of Agricultural Sciences Uppsala and 2Swedish Dairy Association Eskilstuna Sweden and department of Physiology Institute for Animal Science and Animal Behaviour Neustadt Germany. Konigsson K Kask K Gustafsson H Kindahl H Parvizi N 15-Ketodihydro-PGF2a progesterone and cortisol profiles in heifers after induction of parturition by injection of dexamethasone. Acta vet. scand. 2001 42 151-159. - In order to study rapid changes in 15-ketodihydro-PGF2a cortisol and progesterone in the period preceding parturition in cattle pre-term parturition was induced in 4 late pregnant heifers. Parturitions were induced by 2 intramuscular injections of 20 mg dexamethasone with a 24-h interval. The first injection was made on days 254 258 264 and 265 in gestation respectively. Twenty-four h before the first injection an intravenous polyurethane cannula was inserted. Blood samples were collected at least every hour until 12 h after parturition and during the second stage of labour at least 6 times per hour. Plasma was analysed for 15-ketodihydro-PGF2a and progesterone by radioimmunoassays and for cortisol by an ELISA. The average time from injection to parturition was days mean range . Two of the heifers had retained foetal membranes RFM . At the start of the experiment the levels of PGF2a metabolite were low 300 pmol L and increased slowly to levels between 1000 and 2000 pmol L at one day before parturition. During the last day however the levels increased rapidly and the highest levels 10000 pmol L were reached at the time of delivery. No pulsatile release was seen. Immediately after foetal expulsion the PG-metabolite levels decreased rapidly

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