tailieunhanh - Effects of temperature on enzyme catalyzed reactions

Living processes consists almost entirely of biochemical reactions. Without catalysts these reactions would not occur fast enough to sustain does an enzyme do this? ------ because enzyme is a catalytic protein-a chemical agent that changes the rate of a reaction without being consumed by the reaction | Effects of temperature on enzyme catalyzed reactions Lecturer: Msc. Le Hong Phu The same with inorganic reactions, the velocity of enzyme-catalyzed reactions increases when temperature increases and decreases if temperature decreases. However, if the temperature increases over the optimum temperature, the velocity of enzyme-catalyzed reactions will decrease very fast while most inorganic reactions don’t have this phenomenon. GROUP’S MEMBER Trần Lê Đan Hà BT070026 Mã Bích Như BT070153 Tô Bảo Châu BT070011 Lê Phương An BT070004 Bùi Nhất Tiên BT070079 CONTENT Introduction Effects of temperature on enzyme-catalyzed reactions Example and Application Conclusion Living processes consists almost entirely of biochemical reactions. Without catalysts these reactions would not occur fast enough to sustain life. How does an enzyme do this? ------> because enzyme is a catalytic protein-a chemical agent that changes the rate of a reaction without being consumed by the reaction Introduction about | Effects of temperature on enzyme catalyzed reactions Lecturer: Msc. Le Hong Phu The same with inorganic reactions, the velocity of enzyme-catalyzed reactions increases when temperature increases and decreases if temperature decreases. However, if the temperature increases over the optimum temperature, the velocity of enzyme-catalyzed reactions will decrease very fast while most inorganic reactions don’t have this phenomenon. GROUP’S MEMBER Trần Lê Đan Hà BT070026 Mã Bích Như BT070153 Tô Bảo Châu BT070011 Lê Phương An BT070004 Bùi Nhất Tiên BT070079 CONTENT Introduction Effects of temperature on enzyme-catalyzed reactions Example and Application Conclusion Living processes consists almost entirely of biochemical reactions. Without catalysts these reactions would not occur fast enough to sustain life. How does an enzyme do this? ------> because enzyme is a catalytic protein-a chemical agent that changes the rate of a reaction without being consumed by the reaction Introduction about enzyme-catalyzed reaction. Optimal temperature of human enzyme is about 35-40ºC, of bacteria is about 70ºC or higher Factor effects on enzyme-catalyzed reaction Fig 1. 32. Examples of interactions contributing to the tertiary structure of a protein. Hydrophobic side chains usually end up in the interior of a protein, away from water. Along with this clustering of hydrophobic groups, misleadingly called hydrophobic interactions, hydrogen bonds, ionic bonds, and van der Waals interactions are all weak interactions (weak bonds) between side chains that collectively hold the protein in a specific conformation. Much stronger are the disulfide bridges, covalent bonds between the side chains of two cysteine amino acids. This diagram shows only one small part of a hypothetical protein. Low temperatures slow the rate of formation of the enzyme-substrate complex because the molecules move at slower speeds and so do not come in contact with one another as frequently. As the temperature rises,

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