tailieunhanh - Báo cáo y học: "Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients. | Li et al. Respiratory Research 2011 12 95 http content 12 1 95 RESPIRATORY RESEARCH RESEARCH Open Access Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients Jing Li 1 Ying Huang2 Xiaoping Lin3 Deyu Zhao4 Guolin Tan5 Jinzhun Wu6 Changqing Zhao7 Jing Zhao8 Michael D Spangfort9 Nanshan Zhong1 and for China Alliance of Research on Respiratory Allergic Disease CARRAD Abstract Background The association between sensitizations and severity of allergic diseases is controversial. Objective This study was to investigate the association between severity of asthma and rhinitis and degree of specific allergic sensitization in allergic patients in China. Method A cross-sectional survey was performed in 6304 patients with asthma and or rhinitis from 4 regions of China. Patients completed a standardized questionnaire documenting their respiratory and allergic symptoms their impact on sleep daily activities school and work. They also underwent skin prick tests with 13 common aeroallergens. Among the recruited subjects 2268 provided blood samples for serum measurement of specific IgE sIgE against 16 common aeroallergens. Results Significantly higher percentage of patients with moderate-severe intermittent rhinitis were sensitized to outdoor allergens while percentage of patients sensitized to indoor allergens was increased with increasing severity of asthma. Moderate-severe intermittent rhinitis was associated with the skin wheal size and the level of sIgE to Artemisia vulgaris and Ambrosia artemisifolia p . Moderate-severe asthma was associated with increasing wheal size and sIgE response to Dermatophagoides D. pteronyssinus and D. farinae p . Moderate-severe rhinitis and asthma were also associated with increase in number of positive skin prick test and sIgE. Conclusions Artemisia vulgaris and Ambrosia artemisifolia sensitizations are associated with the severity of intermittent .

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